Kleen Lab at UCSF
We use computational neuroscience, machine learning, and signal processing to understand neural activity related to cognition and epilepsy
Investigating Data From the Source
Recordings directly from brain tissue give us a rare and incredible window into understanding both normal and abnormal neural activity.
Deciphering neural code
We use signal processing techniques and machine learning to understand human brain activity
Neural Activity Flow
We investigate how brain waves move through space and time, across the entire brain or important brain structures like the hippocampus
Visualizing Seizures in the Brain
We develop new #dataviz (data visualization) approaches to help doctors understand how seizures spread through the brain of individual patients
Location
We are located at the Parnassus Campus of UCSF Medical Center, a global leader in clinical care and cutting edge research based in the heart of our incredible city, San Francisco.

Overview

The Kleen Lab is based in the Division of Epilepsy, and Department of Neurology, at the University of California San Francisco (UCSF). Jon Kleen MD PhD is the principal investigator and a neurologist, epileptologist and neuroscientist.

Our clinical and translational research program uses emerging technologies in computer science to make new discoveries about memory and cognition in humans, and how neurological diseases disrupt these crucial functions. 

We are humbled to work closely with leaders in human neurophysiology, bioengineering, computer science, and more. Together, we are advancing the understanding of neural processes that support the incredible cognitive abilities that define us as human beings, and developing new approaches to rescue them from disease.

Central Initiatives:

Neurophysiology of human memory

Cognitive impairment due to neurological disease

Neural activity flow in space and time

 

 

Kleen Lab